Listing of research core items
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Instrument/equipment
BD Symphony S6 cell sorter
Sort into 5 mL round tubes, 15 mL conical tubes, or plates (24-, 48-, and 96-well) with 5 lasers (UV, violet, blue, yellow/green, red) and 23 detectors (6 UV, 6 violet, 4 blue, 4 yellow/green, 3 red).
Located within West Campus Flow Cytometry Facility -
Instrument/equipment
Flow cytometry cell sorting
Learn more about cell sorting at Yale Flow Cytometry Facility.
Located within Yale Flow Cytometry Facility -
Core/facility
Yale Center for Genome Analysis (YCGA)
The Yale Center for Genome Analysis is a full-service facility dedicated to providing RNA expression profiling, DNA genotyping, and high-throughput sequencing using state-of-the-art technologies.
General inquiries
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Core/facility
Yale Center for Molecular Discovery
We provide resources for assay development and high-throughput screening with small molecules and arrayed siRNA and sgRNA/CRISPR libraries in biochemical, cell-based and image-based assays (primarily 384-well format).
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Core/facility
Chemical Metabolism Core
Previously called the Islet, Oxygen consumption, Mass Isotopomer flux Core (IOMIC), the Chemical Metabolism Core offers targeted and untargeted metabolomics, stable isotope-based metabolic flux analysis, quantitative metabolic panels of central carbon metabolism and adjacent pathways, measurements of cellular bioenergetics, islet isolation and functional studies. Services include study assistance and data analysis.
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Instrument/equipment
Chemical vapor deposition
The chemical vapor deposition (CVD) tools can deposit metal, oxide, and nitride thin films. The cleanroom offers various CVD tools, including plasma-enhanced CVD and atomic layer deposition.
Located within Yale Cleanroom Facilities -
Core/facility
Yale Cleanroom Facilities
The University Cleanroom provides a controlled environment that maintains intentionally low concentrations of pollutants to allow for uncontaminated scientific research.
Yong Sun & Lauren McCabe
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Core/facility
CMC Live-Cell Imaging Core (CLIC)
Affiliated with the Chemical Metabolism Core (CMC), the Live Cell Imaging Core (CLIC) offers assessments of metabolites, live-cell imaging, biosensor design and delivery, perfusion assays, a library of dyes and biosensors, and more.
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Services
Comparative Pathology Research (CPR) Support
Expertise in the evaluation, diagnosis, and documentation of macroscopic, microscopic, ultrastructural, and clinical pathologic findings in rodents and other species.
Located within Comparative Pathology Research Core -
Core/facility
Comparative Pathology Research Core
We offer pathology support for animal-based studies, including histopathology, necropsy, and microbiology, as well as assistance with study design.
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Core/facility
Confocal Microscopy at CCMI
We offer confocal microscopy, two-photon microscopy, light-sheet microscopy, swept-field microscopy, super-resolution imaging, and image analysis services.
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Services
Genome editing using CRISPR/Cas9 technique
Gene knockout, single or a few nucleotides replacement and insert reporters in specific locus in hESCs and iPSCs using CRISPR/Cas9 technology.
Located within Human Embryonic/Induced Pluripotent Stem Cell Core