Listing of research core items
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Core/facility
Comparative Pathology Research Core
We offer pathology support for animal-based studies, including histopathology, necropsy, and microbiology, as well as assistance with study design.
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Core/facility
Confocal Microscopy at CCMI
We offer confocal microscopy, two-photon microscopy, light-sheet microscopy, swept-field microscopy, super-resolution imaging, and image analysis services.
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Services
Genome editing using CRISPR/Cas9 technique
Gene knockout, single or a few nucleotides replacement and insert reporters in specific locus in hESCs and iPSCs using CRISPR/Cas9 technology.
Located within Human Embryonic/Induced Pluripotent Stem Cell Core -
Core/facility
Yale CryoEM Resource
The Yale CryoEM Resource comprises electron microscopes on all 3 campuses: a Titan Krios on West Campus, a Glacios and a Tecnai T12 at Yale School of Medicine, and a Glacios and a Talos L120C on Science Hill.
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Core/facility
Yale CVRC Micro-CT Imaging Core
Dedicated to assisting translation of scientific discoveries from benches to rodent models and to facilitate development of new contrast agents and therapeutic agents.
Zhen Zhuang, MD, MS
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Core/facility
CyTOF Facility
Time-of-flight mass spectrometer for multi-parametric single cell data
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Core/facility
Yale University Cytogenetics Laboratory
The core provides testing for cancer predisposition, metabolic and developmental disorders.
DNA Diagnostics Lab
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Instrument/equipment
Differential scanning calorimetry (DSC)
This instrument measures the heat flow of materials across phase transitions. Technical specifications and limits of the equipment are listed below.
Located within Mechanical and Thermal Analysis Instrumentation Core (MTAIC) -
Core/facility
Keck DNA Sequencing Facility
Keck DNA Sequencing provides Sanger sequencing and other services, with costs starting as low as $2.22/well and $4.00/tube submission. Sequencing is performed using Thermo Fisher technologies.
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Services
DNA/RNA QC analysis service
QC using the Agilent TapeStation 2200 allows researchers to analyze the quantity and size of DNA or RNA while using only a few microliters of precious sample.
Located within Keck DNA Sequencing FacilityKeck DNA Sequencing
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Instrument/equipment
Dry and plasma etching
Dry and plasma etching tools provide the capability to etch metals, semiconductors, and organic films at controllable rates with high selectivity.
Located within Yale Cleanroom Facilities -
Core/facility
Earth Materials Characterization Center (EMC2)
We offer materials physics equipment including microscopy, spectroscopy, deformation tools, and sample-prep tools for sample characterization work.