Cores Directory

Search for the resources you need to answer your research questions.

219 results found

Listing of research core items

  1. Instrument/equipment

    Mass spectrometry

    Instruments for mass spectrometry

    Terence Wu

    Director
  2. Instrument/equipment

    Super-resolution and confocal microscopes

    Learn about our Abberior STEDYCON, Andor BC43, Leica SP8, Leica Stellaris 8 Falcon, and Nikon CSU-W1.
     

    Located within West Campus Imaging Core

    Joerg Nikolaus, PhD

    Director
  3. Instrument/equipment
    Stirring apparatus

    High-throughput mixing and stirring

    If you need to mix or stir blocks of many reactions, we have several solutions available for running reactions from -10 to 180 °C.

    Manisha Skaria

    Director
  4. Instrument/equipment

    Plate pressure reactor

    From V&P Scientific, this reactor allows for screening up to 48 reactions in GC vials at pressures up to 300 PSIG. Reactions have a shared headspace.

    Manisha Skaria

    Director
  5. Instrument/equipment

    Savant SpeedVac

    This centrifugal evaporator is designed for parallel evaporation of vials and plates. The incorporated condensing trap eliminates the need for cold baths.

    Manisha Skaria

    Director
  6. Instrument/equipment
    NMR tube

    High-pressure NMR tubes

    These NMR tubes are made from PEEK polymer and capable of withstanding pressures up to 500 PSI. Used for work in with spectrometers in the CBIC.

    Manisha Skaria

    Director
  7. Instrument/equipment
    Digital pipette lying on a counter

    Eppendorf pipettes

    We have a variety of Eppendorf micropipettes. Manual and electronic single- and multi-channel pipettes allow for rapid dispensing of simple plate designs.

    Manisha Skaria

    Director
  8. Instrument/equipment

    Light sheet microscope

    Miltenyi UM Blaze is a a user-friendly light sheet microscope designed for subcellular 3D imaging of large and multiple samples.

    Located within West Campus Imaging Core

    Joerg Nikolaus, PhD

    Director
  9. Services
    Two scientists look at a computer screen

    Metabolic flux and enrichment studies using MIMOSA

    In this subcore, parameters of cellular and tissue metabolic flux are assessed by incorporation of stable isotope-labeled tracers (e.g., carbon-13, nitrogen-15, or deuterium) into metabolism. The CMC uses the targeted mass isotopomer multi-ordinate spectral analysis (MIMOSA) platform to interpret stable isotope labeling patterns for calculation of rates of discrete steps in glycolytic and mitochondrial metabolism. Such measurements can be used to identify differences in fuel usage (e.g., glycolysis vs. beta-oxidation), and non-oxidative (reductive carboxylation, anaplerosis and cataplerosis) contributions to the TCA cycle.

    Located within Chemical Metabolism Core

    Stephan Siebel, MD, PhD

  10. Instrument/equipment

    NMR

    Our NMR instruments include a Bruker 400 MHz broadband probe and an Agilent DD2 600 MHz 3 mm cold probe.

    Terence Wu

    Director
  11. Instrument/equipment

    Biotechnology

    Biotechnology instruments

    Terence Wu

    Director
  12. Instrument/equipment

    Other microscopes

    Learn about our Leica DMi8 epifluorescence, Leica Thunder Imager 3D epifluorescence, Leica LMD7000 laser microdissection, and Leica M125 stereo microscopes and Thorlabs optical tweezers system.
     

    Located within West Campus Imaging Core

    Joerg Nikolaus, PhD

    Director