Cores Directory
Search for the resources you need to answer your research questions.
Listing of research core items
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Core/facility
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Services
Comparative Pathology Research (CPR) Support
Expertise in the evaluation, diagnosis, and documentation of macroscopic, microscopic, ultrastructural, and clinical pathologic findings in rodents and other species.
Located within Comparative Pathology Research Core -
Core/facility
Comparative Pathology Research Core
We offer pathology support for animal-based studies, including histopathology, necropsy, and microbiology, as well as assistance with study design.
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Core/facility
Yale Genome Editing Center
We create genetically engineered mice via CRISPR/Cas, gene targeting via homologous recombination in ES cells, and traditional transgenic technology. We also cryopreserve mouse sperm and embryos.
Timothy Nottoli, PhD
Co-Director Research Scientist in Comparative Medicine -
Services
Histology Service
Preparation of animal tissues for microscopic examination.
Located within Comparative Pathology Research Core -
Services
In vivo cancer models
Cell line-derived xenograft (CDX) models, patient-derived xenograft (PDX) models, syngeneic models, genetically engineered mouse models (GEMMS), metastasis models.
Located within Precision Cancer ModelingVish Muthusamy, PhD
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Services
Microbiology Service
Bacterial culture, identification, optional antibiotic sensitivity and resistance, and fungal isolation from animal specimens.
Located within Comparative Pathology Research Core -
Services
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Core/facility
Precision Cancer Modeling
We help enable well-designed, scientifically sound preclinical studies for drug development. We offer custom in vivo cancer models best suited for pharmacological evaluation of experimental therapies.
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Services
Preclinical studies
Drug formulation, toxicology, pharmacokinetics, pharmacodynamics, and non-cancer pharmacodynamics/efficacy studies.
Located within Precision Cancer ModelingVish Muthusamy, PhD
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Services
Whole mouse phenotyping
Macroscopic (gross) and histopathologic (microscopic) evaluation.
Located within Comparative Pathology Research CoreCarmen Jane Booth, DVM, PhD
Director of Comparative Pathology Research -
Instrument/equipment
Equipment
We have several pieces of equipment that can be booked for general use. Core staff needs to take priority on any equipment and bookings can be preempted at our discretion.
Located within Yale Zebrafish Research Core