Listing of research core items
-
Instrument/equipment
-
Services
Cellular and mitochondrial respiration and bioenergetics
Cellular and mitochondrial respiration are assessed with the Agilent Seahorse XF Pro. In a 96-well plate format, real-time measurements of cellular respiration, oxidative phosphorylation, mitochondrial leak, and mitochondrial transport are assessed as functional kinetic measurements of cellular bioenergetics. An integrated Agilent BioTek Cytation5 imager correlates cell number to respiration for more accurate normalization of respiration.
Located within Chemical Metabolism CoreRebecca Cardone, MS
-
Core/facility
Aberration-Corrected Electron Microscopy (ACEM) Core
Our core's focus is cutting-edge and high-throughput capability in electron microscopy techniques, including TEM, SEM, and FIB.
-
Instrument/equipment
Abrasive water jet cutting
The high-pressure abrasive water jet cutter can be best thought of as a computer-controlled bandsaw. It is largely used to cut through flat material stock.
Located within Advanced Prototyping Center at Wright LabJames A. Nikkel, PhD
-
Core/facility
Advanced Prototyping Center at Wright Lab
The Advanced Prototyping Center is a fabrication and design support facility to help Yale researchers with custom instrumentation.
-
Core/facility
Yale Analytical and Stable Isotope Center (YASIC)
Our analytical services include measurements of stable and radiocarbon isotopes, cations, anions, greenhouse gases, natural γ-radiation, mercury, and nutrients in water or soil extracts.
-
Core/facility
-
Instrument/equipment
Invitrogen Attune NXT Cell Analyzer
Analyze cells from tubes and plates with 4 lasers (violet, blue, yellow/green, red) and 14 detectors (6 violet, 2 blue, 3 yellow, 3 red).
Located within West Campus Flow Cytometry Facility -
Instrument/equipment
Back-end processing
The cleanroom offers tools for the back-end processing of device fabrication, including a critical-point dryer and scribing and dicing tools, as well as lapping and polishing tools.
Located within Yale University Cleanroom -
Core/facility
Keck Bioinformatics Resource
The Bioinformatics Resource offers software support; consultation on DNA/protein sequence, microarray, protein structure, and pathway analysis; and collaboration.
Contact
-
Core/facility
Keck Biophysical Resource
We offer resources to study the oligomeric state of biomolecular assemblies as well as the thermodynamics and kinetics of macromolecular interactions.
-
Core/facility
Keck Biostatistics Resource
We offer consultation related to statistical and computational analysis of various types of biological and biomedical data, such as gene expression, genotyping, mass spectrometry, and next-generation sequencing.