Cores Directory

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247 results found

Listing of research core items

  1. Instrument/equipment
    Helios G4 UX tool

    Helios G4 UX DualBeam System

    Helios G4 UX DualBeam (electron & ion-beam) microscope

    Located within Aberration-Corrected Electron Microscopy (ACEM) Core

    ACEM Core

    Director
  2. Services

    Histology Service

    Preparation of animal tissues for microscopic examination.

    Located within Comparative Pathology Research Core

    Michael Schadt & AJ Nugent

    Manager Histotechnologist
  3. Instrument/equipment

    Hitachi IM 4000 ion milling

    The IM4000II supports both cross-section milling and flat-milling to prepare specimens, depending on the purpose.

    Located within Earth Materials Characterization Center (EMC2)

    Zhenting Jiang

    Laboratory Manager
  4. Services
    CLA Spotting Cards

    Human cell line authentication

    Using a cell line authentication service can help to establish the identity of a cell line or confirm that it remains uncontaminated. With the use of the CLA Identifiler Direct Kit, we will perform STR genotyping by fragment analysis. This STR profile will be the key to authenticating the cell line.

    Located within Keck DNA Sequencing Facility

    dnaseq@yale.edu

  5. Core/facility

    Human Embryonic/Induced Pluripotent Stem Cell Core

    We provide essential services for research on human embryonic stem cells (hESCs) and human induced pluripotent stem cells (iPSCs).

    Caihong Qiu, PhD

    Technical Director
  6. Services

    Imaging services

    Micro-CT, pulse Doppler, and imaging analysis.

    Located within Yale CVRC Micro-CT Imaging Core

    Zhen Zhuang, MD, MS

  7. Instrument/equipment

    Imaris image analysis workstations

    Imaris imaging analysis workstations

    Located within Confocal Microscopy at CCMI

    Mateus Guerra, PhD

    Primary contact
  8. Services

    In vitro assays and cancer models

    3D and explant cultures, cytotoxicity assays, and immunoassays.

    Located within Precision Cancer Modeling

    Vish Muthusamy, PhD

  9. Services

    In vivo cancer models

    Cell line-derived xenograft (CDX) models, patient-derived xenograft (PDX) models, syngeneic models, genetically engineered mouse models (GEMMS), metastasis models.
     

    Located within Precision Cancer Modeling

    Vish Muthusamy, PhD

  10. Instrument/equipment

    In vivo imaging

    The PCM provides user access to in vivo imaging instruments housed within imaging clusters at two campus locations. These instruments are available for independent user operation following completion of required instrument and regulatory training.

    Located within Precision Cancer Modeling

    Vish Muthusamy, PhD

  11. Core/facility

    In Vivo Imaging (IVI) Facility

    The core offers researchers access to an upright two-photon laser scanning microscope optimized for in vivo fluorescence imaging studies. Training or direct staff assistance is available in surgical preparations, imaging acquisition, and data analysis.

    David Gonzalez, MHS LAT

    Facility Manager
  12. Services

    Induced pluripotent stem cell (iPSC) production

    We reprogram fully differentiated somatic cells to induced pluripotent stem cells (iPSCs).

    Located within Human Embryonic/Induced Pluripotent Stem Cell Core

    Caihong Qiu, PhD

    Technical Director