Cores Directory

Search for the resources you need to answer your research questions.

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219 results found

Listing of research core items

  1. Services
    CLA Spotting Cards

    Human cell line authentication

    Using a cell line authentication service can help to establish the identity of a cell line or confirm that it remains uncontaminated. With the use of the CLA Identifiler Direct Kit, we will perform STR genotyping by fragment analysis. This STR profile will be the key to authenticating the cell line.

    Located within Keck DNA Sequencing Facility

    dnaseq@yale.edu

  2. Core/facility

    Human Embryonic/Induced Pluripotent Stem Cell Core

    We provide essential services for research on human embryonic stem cells (hESCs) and human induced pluripotent stem cells (iPSCs).

    Caihong Qiu, PhD

    Technical Director
  3. Instrument/equipment

    Imaris image analysis workstations

    Imaris imaging analysis workstations

    Located within Confocal Microscopy at CCMI

    Mateus Guerra, PhD

    Primary contact
  4. Services

    In vitro assays and cancer models

    3D and explant cultures, cytotoxicity assays, and immunoassays.

    Located within Precision Cancer Modeling

    Vish Muthusamy, PhD

  5. Services

    In vivo cancer models

    Cell line-derived xenograft (CDX) models, patient-derived xenograft (PDX) models, syngeneic models, genetically engineered mouse models (GEMMS), metastasis models.
     

    Located within Precision Cancer Modeling

    Vish Muthusamy, PhD

  6. Instrument/equipment

    In vivo imaging

    The PCM provides user access to in vivo imaging instruments housed within imaging clusters at two campus locations.

    Located within Precision Cancer Modeling

    Vish Muthusamy, PhD

  7. Core/facility

    In Vivo Imaging (IVI) Facility

    The core offers researchers access to an upright two-photon laser scanning microscope optimized for in vivo fluorescence imaging studies. Training or direct staff assistance is available in surgical preparations, imaging acquisition, and data analysis.

    David Gonzalez, MHS LAT

    Facility Manager
  8. Services

    Induced pluripotent stem cell (iPSC) production

    We reprogram fully differentiated somatic cells to induced pluripotent stem cells (iPSCs).

    Located within Human Embryonic/Induced Pluripotent Stem Cell Core

    Caihong Qiu, PhD

    Technical Director
  9. Instrument/equipment
    Instron

    Instron tensile/compression testing

    This instrument performs tensile, compression, flexure/bend, peel, tear, shear, and cyclic tests.

    Located within Mechanical and Thermal Analysis Instrumentation Core (MTAIC)

    Amit Datye, PhD

    Primary Contact
  10. Instrument/equipment

    Instruments for sample preparation

    The core houses multiple cryo-sample preparation devices.

    Located within Yale CryoEM Resource

    Jianfeng Lin, PhD

    Managing Director
  11. Instrument/equipment

    Ion mill

    The Hitachi IM4000 can be used for cross-sectioning samples (usually for SEM viewing) or for polishing surfaces.

    Located within Yale Institute for Nanoscience and Quantum Engineering (YINQE)

    Sungwoo Sohn, PhD

    Associate Director of Facilities
  12. Instrument/equipment

    Iridium sputtering tool

    Iridium is useful for coating samples before electron microscopy.

    Located within Yale Institute for Nanoscience and Quantum Engineering (YINQE)

    Sungwoo Sohn, PhD

    Associate Director of Facilities