Instrument design & electronics prototyping
About the services
Instrument design
We have designed instruments and parts for groups across campus and across disciplines. Contact us for more information about how we can support your project.
Electronics prototyping
For prototyping and development of electronics, we have developed various systems using micro-controllers and basic FPGAs for integration into larger projects. Contact us.
Examples include:
- Motor/servo control
- Environmental monitoring
- Detector readout
- Database integration
Available to Yale researchers only
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Instrument/equipment
Electron-beam lithography
For nanoscale patterning, the Raith EBPG 5000+ and EBPG 5200+ electron-beam lithography systems provide 100kV patterning of 10 nm scale devices.
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Instrument/equipment
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Services
Metabolic flux and enrichment studies using MIMOSA
In this subcore, parameters of cellular and tissue metabolic flux are assessed by incorporation of stable isotope-labeled tracers (e.g., carbon-13, nitrogen-15, or deuterium) into metabolism. The CMC uses the targeted mass isotopomer multi-ordinate spectral analysis (MIMOSA) platform to interpret stable isotope labeling patterns for calculation of rates of discrete steps in glycolytic and mitochondrial metabolism. Such measurements can be used to identify differences in fuel usage (e.g., glycolysis vs. beta-oxidation), and non-oxidative (reductive carboxylation, anaplerosis and cataplerosis) contributions to the TCA cycle.
Located within Chemical Metabolism CoreStephan Siebel, MD, PhD