Cores Directory

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Listing of research core items

  1. Services
    Fragment Analysis

    Fragment analysis

    Our 3730XL DNA Analyzer uses fluorescence-based detection to determine the size of DNA fragments. 

    Located within Keck DNA Sequencing Facility

    dnaseq@yale.edu

  2. Instrument/equipment

    Functional near-infrared spectroscopy (fNIRS)

    Functional near-infrared spectroscopy (fNIRS) is a portable technique that uses near-infrared light to estimate cortical hemodynamic activity related to neural activity. 

    Located within BrainWorks

    Roeland Hancock

    Director
  3. Instrument/equipment
    Helios G4 UX tool.

    Helios G4 UX DualBeam System

    Helios G4 UX DualBeam (electron & ion-beam) microscope

    Located within Aberration-Corrected Electron Microscopy (ACEM) Core

    ACEM Core

    Director
  4. Services
    CLA Spotting Cards

    Human cell line authentication

    Using a cell line authentication service can help to establish the identity of a cell line or confirm that it remains uncontaminated. With the use of the CLA Identifiler Direct Kit, we will perform STR genotyping by fragment analysis. This STR profile will be the key to authenticating the cell line.

    Located within Keck DNA Sequencing Facility

    dnaseq@yale.edu

  5. Instrument/equipment

    Imaris image analysis workstations

    Imaris imaging analysis workstations

    Located within Confocal Microscopy at CCMI

    Mateus Guerra, PhD

    Primary contact
  6. Core/facility

    In Vivo Imaging (IVI) Facility

    The core offers researchers access to an upright two-photon laser scanning microscope optimized for in vivo fluorescence imaging studies. Training or direct staff assistance is available in surgical preparations, imaging acquisition, and data analysis.

    David Gonzalez, MHS LAT

    Facility Manager
  7. Instrument/equipment

    Ion mill

    The Hitachi IM4000 can be used for cross-sectioning samples (usually for SEM viewing) or for polishing surfaces.

    Located within Yale Institute for Nanoscience and Quantum Engineering (YINQE)

    Sungwoo Sohn, PhD

    Associate Director of Facilities
  8. Instrument/equipment

    Iridium sputtering tool

    Iridium is useful for coating samples before electron microscopy.

    Located within Yale Institute for Nanoscience and Quantum Engineering (YINQE)

    Sungwoo Sohn, PhD

    Associate Director of Facilities
  9. Core/facility

    Keck Mass Spectrometry & Proteomics Resource

    We provide efficient and cost-effective proteomics and state-of-the-art small-molecule mass spectrometry-based services.

    TuKiet Lam, PhD

    Director
  10. Core/facility

    Keck Microarray Shared Resource

    Microarray platforms available for high-throughput gene-expression detection.

    Guilin Wang, PhD

    Primary contact
  11. Instrument/equipment

    Keck Microarray instrumentation

    Tools for nucleic acid isolation and assessment, microarray genotyping and gene expression profiling, single-cell genomics and proteomics analysis, spatial genomics analysis, and long-read sequencing.

    Located within Keck Microarray Shared Resource

    Primary contact

  12. Instrument/equipment

    Leica SP5 confocal microscope

    Leica SP5 confocal microscope

    Located within Confocal Microscopy at CCMI

    Mateus Guerra, PhD

    Primary contact Associate Director