Cores Directory
Search for the resources you need to answer your research questions.
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Listing of research core items
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Services
Genome editing using CRISPR/Cas9 technique
Gene knockout, single or a few nucleotides replacement and insert reporters in specific locus in hESCs and iPSCs using CRISPR/Cas9 technology.
Located within Human Embryonic/Induced Pluripotent Stem Cell Core -
Core/facility
CyTOF Facility
The CyTOF 2 facility houses a time-of-flight atomic mass spectrometer for the high-speed acquisition of highly multi-parametric single-cell data.
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Core/facility
Yale University Cytogenetics Laboratory
The core provides testing for cancer predisposition, metabolic and developmental disorders.
DNA Diagnostics Lab
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Core/facility
Keck DNA Sequencing Facility
Keck DNA Sequencing provides Sanger sequencing and other services, with costs starting as low as $1.99/well and $3.50/tube submission. Sequencing is performed using Thermo Fisher technologies.
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Services
DNA/RNA QC analysis service
QC using the Agilent Tapestation 2200 allows researchers to analyze the quantity and size of DNA or RNA while using only a few microliters of precious sample.
Located within Keck DNA Sequencing FacilityKeck DNA Sequencing
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Core/facility
Electron Microscopy Facility at CCMI
The Electron Microscopy Facility at the Center for Cellular and Molecular Imaging (CCMI) provides investigators with a wide range of electron microscopy services.
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Instrument/equipment
Cytek Aurora Spectral Cell Analyzer
Analyze from single tubes, 40-tube racks, or 96-well plates with 5 lasers (UV, violet, blue, yellow/green, red) and 64 detectors (16 UV, 16 violet, 14 blue, 10 yellow/green, 8 red).
Located within West Campus Flow Cytometry Facility -
Instrument/equipment
BD FACS Aria Cell Sorter
Sort into 5 mL round tubes, 15 mL conical tubes, or plates (24-, 48-, or 96-well) with 4 lasers (violet, blue, yellow/green, red) and 14 detectors (6 violet, 2 blue, 4 yellow/green, 2 red).
Located within West Campus Flow Cytometry Facility -
Core/facility
FIB-SEM Collaboration Core (F-SCC)
We utilize unparalleled enhanced FIB-SEM pipeline to generate large-volume three-dimensional electron microscopy data with nanometer isotropic resolution. Such data reveal critical insights about structure-function relationships in biology.
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Core/facility
Yale Flow Cytometry Facility
We offer a comprehensive range of services for flow cytometric analysis and sorting, encompassing instrumentation, technical assistance, training, and consultation throughout Yale School of Medicine.
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Instrument/equipment
Flow cytometry analysis
If you are interested in flow cytometry analysis, please visit our onboarding page to create an account in PPMS.
Located within Yale Flow Cytometry Facility -
Core/facility
West Campus Flow Cytometry Facility
We offer training for and access to flow cytometry analyzers and cell sorters.