Yale Center for Genome Analysis (YCGA)
Primary contact
About the core
Located on West Campus, the Yale Center for Genome Analysis (YCGA) offers RNA expression profiling, DNA genotyping, and high-throughput sequencing services.
Services
Next-gen sequencing
- Illumina
- Pacific Biosciences
- 10X Genomics
Microarray
- Affymetrix
- Illumina
Bioinformatics
Three PhD-level scientists provide downstream analysis support of NGS sequencing data, with a focus on whole exome, RNA-seq, ChIP-seq and whole genome analysis. In addition, this group is heavily involved in the development/evaluation and implementation of new analysis pipelines and interacts with High Performance Computation (HPC) group to manage NGS data.
Mendelian genomics
Yale Center for Mendelian Genomics (CMG) applies next-generation sequencing and computational approaches to discover the genes and variants that underlie Mendelian disorders. It provides free exome sequencing and analysis to collaborating investigators for qualified phenotypes.
Available to Yale researchers & external researchers
Core website
Contacts
West Campus Genome Analysis Center
830 West Campus Drive
West Haven, CT 06516
Primary contact
Patient Recruitment Coordinator
Bioinformatics support
Executive Director
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Core/facility
Yale Center for Molecular Discovery
We provide resources for assay development and high-throughput screening with small molecules and arrayed siRNA and sgRNA/CRISPR libraries in biochemical, cell-based and image-based assays (primarily 384-well format).
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Core/facility
Chemical Metabolism Core
Previously called the Islet, Oxygen consumption, Mass Isotopomer flux Core (IOMIC), the Chemical Metabolism Core offers targeted and untargeted metabolomics, stable isotope-based metabolic flux analysis, quantitative metabolic panels of central carbon metabolism and adjacent pathways, measurements of cellular bioenergetics, islet isolation and functional studies. Services include study assistance and data analysis.
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Core/facility
CyTOF Facility
The CyTOF 2 facility houses a time-of-flight atomic mass spectrometer for the high-speed acquisition of highly multi-parametric single-cell data.