Cores Directory

Search for the resources you need to answer your research questions.

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  • It could be microscopy.
  • What tools or support are you looking for?
  • It could be a cleanroom.
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Listing of research core items

  1. Instrument/equipment

    Optical

    Optical instrumentation

    Located within West Campus Analytical Core

    Terence Wu

    Director
  2. Instrument/equipment

    Atomic force microscope

    Asylum Research Cypher AFM

    Located within West Campus Imaging Core

    Joerg Nikolaus, PhD

    Director
  3. Services
    Two scientists examine a monitor

    Cellular and mitochondrial respiration and bioenergetics

    Cellular and mitochondrial respiration (OCR) and acidification (ECAR) are assessed with the Agilent Seahorse XF Pro 96. In a 96-well plate format, real-time measurements of cellular respiration, oxidative phosphorylation, mitochondrial leak, and mitochondrial transport are assessed as functional kinetic measurements of cellular bioenergetics. Changes in acidification are also observed simultaneously. An integrated Agilent BioTek Cytation5 imager correlates cell number via Hoechst nuclear stain to respiration for more accurate normalization of respiration.

    Located within Chemical Metabolism Core

    Rebecca Cardone, MS

  4. Core/facility

    Advanced Instrumentation Development Center (AIDC)

    Our mission stands at the nexus between hardware, computing, and data science.

    AIDC

  5. Core/facility

    Yale Analytical and Stable Isotope Center (YASIC)

    Our analytical services include measurements of stable and radiocarbon isotopes, cations, anions, greenhouse gases, natural γ-radiation, mercury, and nutrients in water or soil extracts.

    Brad Erkkila

    Primary contact Director
  6. Instrument/equipment
    Cell Analyzer

    Invitrogen Attune NXT Cell Analyzer

    Analyze cells from tubes and plates with 4 lasers (violet, blue, yellow/green, red) and 14 detectors (6 violet, 2 blue, 3 yellow, 3 red).

    Located within West Campus Flow Cytometry Facility

    Fiona Hall Fenteany

    WCFC Director
  7. Instrument/equipment

    Back-end processing

    The cleanroom offers tools for the back-end processing of device fabrication, including a critical-point dryer and scribing and dicing tools, as well as lapping and polishing tools.

    Located within Yale University Cleanroom

    Yong Sun

    Director
  8. Core/facility

    Keck Biophysical Resource

    We offer resources to study the oligomeric state of biomolecular assemblies as well as the thermodynamics and kinetics of macromolecular interactions.

    Ewa Folta-Stogniew, PhD, MSc

    Primary contact Director
  9. Core/facility

    Keck Biostatistics Resource

    We offer consultation related to statistical and computational analysis of various types of biological and biomedical data, such as gene expression, genotyping, mass spectrometry, and next-generation sequencing.

    Hongyu Zhao, PhD

    Primary contact Director
  10. Instrument/equipment

    Bruker Luxendo light sheet microscope

    Bruker Luxendo light sheet microscope

    Located within Confocal Microscopy at CCMI

    Mateus Guerra, PhD

    Primary contact Associate Director
  11. Instrument/equipment

    Bruker Opterra II swept-field microscope

    Bruker Opterra II swept-field microscope

    Located within Confocal Microscopy at CCMI

    Mateus Guerra, PhD

    Primary contact Associate Director
  12. Instrument/equipment

    Bruker Vutara 352 super-resolution microscope

    Bruker Vutara 352 super-resolution microscope

    Located within Confocal Microscopy at CCMI

    Mateus Guerra, PhD

    Primary contact Associate Director