Cores Directory
Search for the resources you need to answer your research questions.
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Listing of research core items
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Core/facility
Yale Genome Editing Center
We create genetically engineered mice via CRISPR/Cas, gene targeting via homologous recombination in ES cells, and traditional transgenic technology. We also cryopreserve mouse sperm and embryos.
Timothy Nottoli, PhD
Primary contact Co-Director Research Scientist in Comparative Medicine -
Services
Human cell line authentication
Using a cell line authentication service can help to establish the identity of a cell line or confirm that it remains uncontaminated. With the use of the CLA Identifiler Direct Kit, we will perform STR genotyping by fragment analysis. This STR profile will be the key to authenticating the cell line.
Located within Keck DNA Sequencing Facilitydnaseq@yale.edu
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Core/facility
Keck Mass Spectrometry & Proteomics Resource
We provide efficient and cost-effective proteomics and state-of-the-art small-molecule mass spectrometry-based services.
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Core/facility
Keck Microarray Shared Resource
Microarray platforms available for high-throughput gene-expression detection.
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Instrument/equipment
Keck Microarray instrumentation
Tools for nucleic acid isolation and assessment, microarray genotyping and gene expression profiling, single-cell genomics and proteomics analysis, spatial genomics analysis, and long-read sequencing.
Located within Keck Microarray Shared ResourcePrimary contact
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Core/facility
Molecular and Serological Diagnostics
We test tissues, cells, feces and environmental samples for veterinary viruses, bacteria, parasites, and fungi by polymerase chain reaction (PCR) and reverse transcriptase-PCR (RT-PCR), and mouse and rat sera for viral antibodies.
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Core/facility
Keck Oligo Synthesis Resource
We provide high-quality, timely DNA and RNA synthesis in individual tubes or plates.
Primary contact
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Services
PCR purification
PCR purification for 96-well plate format is available to experienced users who are confident in their methodology for PCR and primer preparation. We purify and sequence your submission.
Located within Keck DNA Sequencing FacilityKeck DNA Sequencing
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Services
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Services
Sanger sequencing
Costs start as low as $1.99/well and $3.50/tube submission. Sequencing performed using Thermo Fisher technologies and can be submitted in tube format or 96-well plate format.
Located within Keck DNA Sequencing FacilityKeck DNA Sequencing
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Core/facility
West Campus Analytical Core
Our instruments help characterize and elucidate the structures of chemical and biophysical samples. We train researchers.
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Core/facility
Yale Plant Growth Facility
The core consists of over 20,000 square feet of greenhouses, growth chambers and workspace for plant genetics, evolutionary biology, climate change, and other controlled-environment research.
Christopher Bolick
Primary contact Associate Director of Research, Marsh Botanical Gardens