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Understanding the World and Shaping Its Future

Through bold thinking, rigorous scholarship, and cross-cutting collaborations, Yale scientific and technological research pushes the boundaries of knowledge to benefit people and our planet.

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Building blocks for breakthroughs

From A(nalytical and stable isotopes) to Z(ebrafish phenotyping), research at Yale combines serious inquiry, deep expertise, and state-of-the-art technology.

Scientists in full-body white coveralls inspect equipment in a cleanroom

Yale’s research cores enable scientists across campus to interact, collaborate, and develop new applications that advance the university’s scientific mission.

A man in a polo shirt stands in front of a poster & talks to someone with the back of their head to the camera

At a series of autumn Cores Fairs, visitors learn how core facilities can help with their research. Mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy are among the offerings at West Campus Analytical Core.  

A bearded man crouches beside a piece of cylindrical equipment

Eric Paulson, PhD, tunes the probe under a nuclear magnetic resonance (NMR) spectrometer, one of twelve at the Chemical and Biophysical Instrumentation Center (CBIC). The Center also houses instruments for mass spectrometry and X-rays.

Micrograph image of a Meissner corpuscle, a sensory organ

A Meissner corpuscle is a group of cells that acts as a touch detector. Its 3D structure was revealed for the first time using enhanced focused ion-beam scanning electron microscopy (FIB-SEM). Image credit: Yury Nikolaev, PhD, a postdoctoral fellow in the Slav Bagriantsev lab.

Microscopic image of liver cancer cells escaping a tumor spheroid in a fibrotic environment.

Liver cancer cells escape a tumor spheroid in a fibrotic environment. This Art in Research contest-winning image was collected by Xiangyu Gong, a postdoctoral associate in the Michael Mak biomedical engineering lab, with a Leica SP8 Confocal microscope.

Research cores make science easier, more fruitful, and more efficient.

“You’d be hard-pressed to find a high-profile experimental research paper from Yale that hasn’t been touched by a core."
Ben Myers Co-Director of Research Cores

Characterizing and elucidating structures

“The WCAC provides our research community here at Yale access to high-level instrumentation, helping to forward discovery.”
Terence Wu Director

Related Research Cores

A more collaborative approach

"One of the most enjoyable aspects of what we do is collaborate with the grad students and faculty to solve the problems they’re up against. It’s not just cranking out the data."
Eric Paulson, PhD Director

Related Research Cores

Cutting-edge electron microscopy

“Potentially, this research will inform the development of tactile sensors for next generation of prosthetics.”
Slav Bagriantsev, PhD Associate Professor, Cellular & Molecular Physiology at Yale School of Medicine

Related Research Cores

New cancer insights

"Compared to cell culture in a petri dish, the three-dimensional models provide new insights into understanding cancer and enable more accurate cancer drug screening. Yale core facilities make it possible for us to unveil novel cellular behaviors in the midst of disease progression."
Xiangyu Gong, PhD Mechanical engineer

Related Research Cores

By the numbers

Yale takes a data-intensive approach to science and technology research, harnessing today's volume, speed, and availability of data to transform knowledge production.

Research Infrastructure

  • 70+ core science facilities
  • 1,169 specialized reference databases
  • 10 campus libraries
  • 15.9 million volumes across Yale's collections

Empowering Support

$1.191B+

in sci/tech R&D expenditures in FY22

HERD Report, 2022

Organizational structures that support excellence Learn more about Yale's scientific research strategy

Newsmakers

Molecular map shows the way towards better food choices

In a new study, Yale researchers used mass spectrometry to examine how different molecules interact with bacteria found in the human gut — an important step towards personalized nutrition tailored to individual gut health needs.

Announcements

NSF CAREER Training Series – Join Us!

The series is designed to support early-career faculty in preparing competitive proposals for the NSF Faculty Early Career Development (CAREER) Program.