Cores Directory

Search for the resources you need to answer your research questions.

79 results found

Listing of research core items

  1. Core/facility

    Keck Biostatistics Resource

    We offer consultation related to statistical and computational analysis of various types of biological and biomedical data, such as gene expression, genotyping, mass spectrometry, and next-generation sequencing.

    Hongyu Zhao, PhD

    Primary contact Director
  2. Instrument/equipment

    Bruker Luxendo light sheet microscope

    Bruker Luxendo light sheet microscope

    Mateus Guerra, PhD

    Primary contact Associate Director
  3. Instrument/equipment

    Bruker Opterra II swept-field microscope

    Bruker Opterra II swept-field microscope

    Mateus Guerra, PhD

    Primary contact Associate Director
  4. Instrument/equipment

    Bruker Vutara 352 super-resolution microscope

    Bruker Vutara 352 super-resolution microscope

    Mateus Guerra, PhD

    Primary contact Associate Director
  5. Core/facility
    Image of fluorescently tagged cells

    Yale Center for Molecular Discovery

    We provide resources for assay development and high-throughput screening with small molecules and arrayed siRNA and sgRNA/CRISPR libraries in biochemical, cell-based and image-based assays (primarily 384-well format).

    Yulia Surovtseva, PhD

    Primary contact Director
  6. Core/facility
    Two masked people in white coats point at a screen in a lab

    Chemical Metabolism Core

    Previously called the Islet, Oxygen consumption, Mass Isotopomer flux Core (IOMIC), the Chemical Metabolism Core offers targeted and untargeted metabolomics, stable isotope-based metabolic flux analysis, quantitative metabolic panels of central carbon metabolism and adjacent pathways, measurements of cellular bioenergetics,  islet isolation and functional studies. Services include study assistance and data analysis.
     

    Stephan Siebel, MD, PhD

    Primary contact Technical Director
  7. Core/facility
    Wet lab fume hoods

    West Campus Cleanroom

    The cleanroom includes 1200 square feet of wet and dry clean laboratories rated at Class 1000, with features standard to most cleanrooms.

    Lauren McCabe, PhD

    Primary contact Assistant Director, Cleanroom
  8. Core/facility
    Microscopic image of tissue at various magnifications

    Confocal Microscopy at CCMI

    We offer confocal microscopy, two-photon microscopy, light-sheet microscopy, swept-field microscopy, super-resolution imaging, and image analysis services.

    Mateus Guerra, PhD

    Primary contact Associate Director
  9. Core/facility

    Yale CryoEM Resource

    The Yale CryoEM Resource comprises electron microscopes on all 3 campuses: a Titan Krios on West Campus, a Glacios and a Tecnai T12 at Yale School of Medicine, and a Glacios and a Talos L120C on Science Hill.

    Jianfeng Lin, PhD

    Primary contact Managing Director
  10. Core/facility
    Person standing before a scientific apparatus

    CyTOF Facility

    The CyTOF 2 facility houses a time-of-flight atomic mass spectrometer for the high-speed acquisition of highly multi-parametric single-cell data.

    Liza Konnikova, MD, PhD

    Primary contact Director
  11. Instrument/equipment
    DSC 250 Zoom In

    Differential scanning calorimetry (DSC)

    This instrument measures the heat flow of materials across phase transitions​. Technical specifications and limits of the equipment are listed below.

    Amit Datye, PhD

    Primary Contact
  12. Instrument/equipment

    Dry and plasma etching

    Oxford 100 RIE-ICP and Glow Research AutoGlow

    Located within West Campus Cleanroom

    Lauren McCabe, PhD

    Primary contact