Cores Directory
Search for the resources you need to answer your research questions.
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Listing of research core items
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Instrument/equipment
Bruker Opterra II swept-field microscope
Bruker Opterra II swept-field microscope
Located within Confocal Microscopy at CCMIMateus Guerra, PhD
Primary contact Associate Director -
Instrument/equipment
Bruker Vutara 352 super-resolution microscope
Bruker Vutara 352 super-resolution microscope
Located within Confocal Microscopy at CCMIMateus Guerra, PhD
Primary contact Associate Director -
Core/facility
Yale Center for Genome Analysis (YCGA)
The Yale Center for Genome Analysis is a full-service facility dedicated to providing RNA expression profiling, DNA genotyping, and high-throughput sequencing using state-of-the-art technologies.
Primary contact
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Core/facility
Yale Center for Molecular Discovery
We provide resources for assay development and high-throughput screening with small molecules and arrayed siRNA and sgRNA/CRISPR libraries in biochemical, cell-based and image-based assays (primarily 384-well format).
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Core/facility
Chemical Metabolism Core
Previously called the Islet, Oxygen consumption, Mass Isotopomer flux Core (IOMIC), the Chemical Metabolism Core offers targeted and untargeted metabolomics, stable isotope-based metabolic flux analysis, quantitative metabolic panels of central carbon metabolism and adjacent pathways, measurements of cellular bioenergetics, islet isolation and functional studies. Services include study assistance and data analysis.
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Core/facility
West Campus Cleanroom
The cleanroom includes 1200 square feet of wet and dry clean laboratories rated at Class 1000, with features standard to most cleanrooms.
Lauren McCabe, PhD
Primary contact Assistant Director, Cleanroom -
Core/facility
Confocal Microscopy at CCMI
We offer confocal microscopy, two-photon microscopy, light-sheet microscopy, swept-field microscopy, super-resolution imaging, and image analysis services.
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Core/facility
Yale CryoEM Resource
The Yale CryoEM Resource comprises electron microscopes on all 3 campuses: a Titan Krios on West Campus, a Glacios and a Tecnai T12 at Yale School of Medicine, and a Glacios and a Talos L120C on Science Hill.
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Core/facility
CyTOF Facility
The CyTOF 2 facility houses a time-of-flight atomic mass spectrometer for the high-speed acquisition of highly multi-parametric single-cell data.
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Core/facility
Yale University Cytogenetics Laboratory
The core provides testing for cancer predisposition, metabolic and developmental disorders.
DNA Diagnostics Lab
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Instrument/equipment
Differential scanning calorimetry (DSC)
This instrument measures the heat flow of materials across phase transitions. Technical specifications and limits of the equipment are listed below.
Located within Mechanical and Thermal Analysis Instrumentation Core (MTAIC) -
Core/facility
Keck DNA Sequencing Facility
Keck DNA Sequencing provides Sanger sequencing and other services, with costs starting as low as $1.99/well and $3.50/tube submission. Sequencing is performed using Thermo Fisher technologies.