Cores Directory

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Listing of research core items

  1. Instrument/equipment
    Photo of a room showing 3 testing computers

    Group behavioral testing

    The BrainWorks Lab for Accelerated Subject Testing (BLAST) provides space for running up 3-6 participants simultaneously in a behavioral paradigm.

    Located within BrainWorks

    Roeland Hancock

    Director
  2. Instrument/equipment

    Bruker Luxendo light sheet microscope

    Bruker Luxendo light sheet microscope

    Located within Confocal Microscopy at CCMI

    Mateus Guerra, PhD

    Primary contact Associate Director
  3. Instrument/equipment

    Bruker Opterra II swept-field microscope

    Bruker Opterra II swept-field microscope

    Located within Confocal Microscopy at CCMI

    Mateus Guerra, PhD

    Primary contact Associate Director
  4. Instrument/equipment

    Bruker Vutara 352 super-resolution microscope

    Bruker Vutara 352 super-resolution microscope

    Located within Confocal Microscopy at CCMI

    Mateus Guerra, PhD

    Primary contact Associate Director
  5. Core/facility
    illustration of genetic code with double helix and base symbols

    Yale Center for Genome Analysis (YCGA)

    The Yale Center for Genome Analysis is a full-service facility dedicated to providing RNA expression profiling, DNA genotyping, and high-throughput sequencing using state-of-the-art technologies.

    Primary contact

  6. Core/facility
    Image of fluorescently tagged cells

    Yale Center for Molecular Discovery

    We provide resources for assay development and high-throughput screening with small molecules and arrayed siRNA and sgRNA/CRISPR libraries in biochemical, cell-based and image-based assays (primarily 384-well format).

    Yulia Surovtseva, PhD

    Director
  7. Core/facility
    Two masked people in white coats point at a screen in a lab

    Chemical Metabolism Core

    Previously called the Islet, Oxygen consumption, Mass Isotopomer flux Core (IOMIC), the Chemical Metabolism Core offers targeted and untargeted metabolomics, stable isotope-based metabolic flux analysis, quantitative metabolic panels of central carbon metabolism and adjacent pathways, measurements of cellular bioenergetics,  islet isolation and functional studies. Services include study assistance and data analysis.
     

    Stephan Siebel, MD, PhD

    Technical Director
  8. Core/facility
    Wet lab fume hoods

    Yale University Cleanroom - West Campus

    The cleanroom at West Campus includes 1200 square feet of wet and dry clean laboratories rated at Class 1000, with features standard to most cleanrooms.

    Lauren McCabe, PhD

    Assistant Director
  9. Core/facility
    Microscopic image of tissue at various magnifications

    Confocal Microscopy at CCMI

    We offer confocal microscopy, two-photon microscopy, light-sheet microscopy, swept-field microscopy, super-resolution imaging, and image analysis services.

    Mateus Guerra, PhD

    Associate Director
  10. Core/facility

    Yale CryoEM Resource

    The Yale CryoEM Resource comprises electron microscopes on all 3 campuses: a Titan Krios on West Campus, a Glacios and a Tecnai T12 at Yale School of Medicine, and a Glacios and a Talos L120C on Science Hill.

    Jianfeng Lin, PhD

    Primary contact Managing Director
  11. Core/facility
    Person standing before a scientific apparatus

    CyTOF Facility

    The CyTOF 2 facility houses a time-of-flight atomic mass spectrometer for the high-speed acquisition of highly multi-parametric single-cell data.

    Liza Konnikova, MD, PhD

    Director
  12. Core/facility

    Yale University Cytogenetics Laboratory

    The core provides testing for cancer predisposition, metabolic and developmental disorders.

    DNA Diagnostics Lab