Catalysis and Separations Core

The CSC is a a new multi-user core facility located in the Chemistry Department at Yale University. Our instruments and laboratory space are in Room 307 of the Class of 1954 Chemistry Research Building. We aim to enable data-centric research in the areas of catalysis and separations. Specifically, we house equipment for high throughput experimentation and analysis, separations of difficult mixtures (both chiral and achiral), and in operando monitoring of chemical reactions. We ask that any prospective users contact the director of the CSC to discuss the capabilities of the center. Requests for instrument training are handled via PPMS.

The core offers a wide variety of scientific instruments to support research in synthetic chemistry, including UHPLC, PrepHPLC, SFC-MS (UPC-MS), EasyMax for parallel reactions, solid and liquid chemical dispensing robots, and other equipment for high-throughput experiments (HTE). Our staff maintains the instruments and provides training in their operation for both new and experienced users.

We provide assistance to researchers in two primary areas: catalysis and separations. 

Catalytic reactions are increasingly important in a wide array of chemical transformations. From polymers to sustainable fuels to organic transformations, studying catalysis is both vital and complex. The CSC provides tools to researchers to study reactions, both using operando and offline analysis methods. Our tools include manual and automated dispensing tools to enable high throughput experimentation, equipment to study reactions at high pressures, and analytical equipment. 

Just as important to understanding chemical reactions is separations. With state-of-the-art chromatography tools, we enable researchers to quickly analyze reaction performance through chiral and achiral separations. Two dimensional chromatographic techniques enable researchers to analyze their reactions even when mixtures are complex. Using all of these tools, the CSC can assist researchers in tackling important and complex research questions.