Cores Directory
Search for the resources you need to answer your research questions.
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Listing of research core items
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Services
Genome editing using CRISPR/Cas9 technique
Gene knockout, single or a few nucleotides replacement and insert reporters in specific locus in hESCs and iPSCs using CRISPR/Cas9 technology.
Located within Human Embryonic/Induced Pluripotent Stem Cell Core -
Core/facility
Yale CryoEM Resource
The Yale CryoEM Resource comprises electron microscopes on all 3 campuses: a Titan Krios on West Campus, a Glacios and a Tecnai T12 at Yale School of Medicine, and a Glacios and a Talos L120C on Science Hill.
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Core/facility
CyTOF Facility
Time-of-flight mass spectrometer for multi-parametric single cell data
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Core/facility
Keck DNA Sequencing Facility
Keck DNA Sequencing provides Sanger sequencing and other services, with costs starting as low as $2.22/well and $4.00/tube submission. Sequencing is performed using Thermo Fisher technologies.
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Services
DNA/RNA QC analysis service
QC using the Agilent TapeStation 2200 allows researchers to analyze the quantity and size of DNA or RNA while using only a few microliters of precious sample.
Located within Keck DNA Sequencing FacilityKeck DNA Sequencing
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Instrument/equipment
Dry and plasma etching
Dry and plasma etching tools provide the capability to etch metals, semiconductors, and organic films at controllable rates with high selectivity.
Located within Yale Cleanroom Facilities -
Core/facility
Earth Materials Characterization Center (EMC2)
We offer materials physics equipment including microscopy, spectroscopy, deformation tools, and sample-prep tools for sample characterization work.
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Core/facility
Electron Microscopy Facility at CCMI
The Electron Microscopy Facility at the Center for Cellular and Molecular Imaging (CCMI) provides investigators with a wide range of electron microscopy services.
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Core/facility
YSM Electronic & Machine Shop
We offer custom design, fabrication, and repair services at the Yale School of Medicine as well as tools for loan. We build prototype devices for medical research.
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Services
Elemental abundance
Services for measuring the abundance of elements in a sample
Located within Yale Analytical and Stable Isotope Center (YASIC) -
Instrument/equipment
EM CCMI instruments
Microscopes, sample preparation, carbon evaporators, and advanced cryo FIB lamella milling for cryo electron tomography.
Located within Electron Microscopy Facility at CCMI -
Services
EM CCMI services
Project consultation and experimental design, sample preparation, and imaging with transmission and scanning electron microscopes.
Located within Electron Microscopy Facility at CCMI