Cores Directory
Search for the resources you need to answer your research questions.
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Listing of research core items
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Core/facility
Yale Center for Genome Analysis (YCGA)
The Yale Center for Genome Analysis is a full-service facility dedicated to providing RNA expression profiling, DNA genotyping, and high-throughput sequencing using state-of-the-art technologies.
Primary contact
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Core/facility
Yale Center for Molecular Discovery
We provide resources for assay development and high-throughput screening with small molecules and arrayed siRNA and sgRNA/CRISPR libraries in biochemical, cell-based and image-based assays (primarily 384-well format).
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Core/facility
Chemical Metabolism Core
Previously called the Islet, Oxygen consumption, Mass Isotopomer flux Core (IOMIC), the Chemical Metabolism Core offers targeted and untargeted metabolomics, stable isotope-based metabolic flux analysis, quantitative metabolic panels of central carbon metabolism and adjacent pathways, measurements of cellular bioenergetics, islet isolation and functional studies. Services include study assistance and data analysis.
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Core/facility
CyTOF Facility
Time-of-flight mass spectrometer for multi-parametric single cell data
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Core/facility
Yale University Cytogenetics Laboratory
The core provides testing for cancer predisposition, metabolic and developmental disorders.
DNA Diagnostics Lab
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Core/facility
Keck DNA Sequencing Facility
Keck DNA Sequencing provides Sanger sequencing and other services, with costs starting as low as $2.22/well and $4.00/tube submission. Sequencing is performed using Thermo Fisher technologies.
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Services
DNA/RNA QC analysis service
QC using the Agilent TapeStation 2200 allows researchers to analyze the quantity and size of DNA or RNA while using only a few microliters of precious sample.
Located within Keck DNA Sequencing FacilityKeck DNA Sequencing
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Services
Fragment analysis
Our 3730XL DNA Analyzer uses fluorescence-based detection to determine the size of DNA fragments.
Located within Keck DNA Sequencing Facilitydnaseq@yale.edu
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Services
Human cell line authentication
Using a cell line authentication service can help to establish the identity of a cell line or confirm that it remains uncontaminated. With the use of the CLA Identifiler Direct Kit, we will perform STR genotyping by fragment analysis. This STR profile will be the key to authenticating the cell line.
Located within Keck DNA Sequencing Facilitydnaseq@yale.edu
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Core/facility
Keck Mass Spectrometry & Proteomics Resource
We provide efficient and cost-effective proteomics and state-of-the-art small-molecule mass spectrometry-based services.
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Core/facility
Keck Microarray Shared Resource
Microarray platforms available for high-throughput gene-expression detection.
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Instrument/equipment
Keck Microarray instrumentation
Tools for nucleic acid isolation and assessment, microarray genotyping and gene expression profiling, single-cell genomics and proteomics analysis, spatial genomics analysis, and long-read sequencing.
Located within Keck Microarray Shared ResourcePrimary contact