Listing of research core items
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Services
Nucleic acid isolation and assessment
DNA/RNA isolation services for a large variety of sample types, including saliva, blood, fresh/frozen or FFPE tissue, and cultured cells.
Located within Keck Microarray Shared ResourcePrimary contact
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Services
Purification
We offer three types of purification.
Located within Keck Oligo Synthesis ResourceContact us
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Services
Microarray genotyping and gene expression profiling
Traditional microarray services to analyze gene expression pattern, DNA sequence polymorphism (SNPs genotyping), and methylation.
Located within Keck Microarray Shared ResourcePrimary contact
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Services
Trityl-ON oligos
The 5’-DMT (trityl) protecting group can be left on the oligo if you would like to use this hydrophobic “handle” for purification.
Located within Keck Oligo Synthesis ResourceContact us
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Services
Modifications
We offer a variety of backbone, internal, 5' terminal, and 3' terminal modifications.
Located within Keck Oligo Synthesis ResourceContact us
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Services
Mixed-base oligos
Order equimolar (degenerate) and non-equimolar (doped) oligos.
Located within Keck Oligo Synthesis ResourceContact us
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Services
RNA & 2'-O-methyl RNA
We synthesize RNA and 2'-O-methyl RNA only at the 1.0 µmole scale.
Located within Keck Oligo Synthesis ResourceContact us
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Services
Single-cell genomics and proteomics analysis
Learn about 10X Genomics, Parse Biosciences, and Bruker Isospark technologies.
Located within Keck Microarray Shared ResourcePrimary contact
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Services
UltraMild synthesis
Some modifications require the use of UltraMild columns, phosphoramidites, and reagents that allow for mild cleavage and deprotection conditions.
Located within Keck Oligo Synthesis ResourceContact us
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Services
Spatial genomics and proteomics analysis
Next-generation molecular profiling solution for classifying tissue based on total mRNA. Morphological context in spatial transcriptomics and spatial proteomics experiments from one slide. 10x Genomics Visium and Nanostring GeoMX.
Located within Keck Microarray Shared ResourcePrimary contact
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Services
Long-read sequencing
Solutions from Oxford Nanopore and PacBio.
Located within Keck Microarray Shared ResourcePrimary contact
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Services
Global metabolomics and integrative -omics (intOmics)
Metabolomics provides screening of targeted (~650) and untargeted (~2500) metabolites.
Located within Chemical Metabolism CoreStephan Siebel, MD, PhD