Services Core/facility: Yale Analytical and Stable Isotope Center (YASIC)

Other YASIC services

  1. Research Cores Directory
  2. Other YASIC services

Brad Erkkila

Director

About the services

#171045Titrator (total alkalinity)

Available to Yale researchers & external researchers

Rates

See rates section on main page. 

Related offerings

More related offerings
  1. Instrument/equipment

    Electron-beam lithography

    For nanoscale patterning, the Raith EBPG 5000+ and EBPG 5200+ electron-beam lithography systems provide 100kV patterning of 10 nm scale devices.

    Located within Yale Institute for Nanoscience and Quantum Engineering (YINQE)

    Sungwoo Sohn, PhD

    Associate Director of Facilities
  2. Instrument/equipment

    Mass spectrometry

    Instruments for mass spectrometry

    Located within West Campus Analytical Core

    Terence Wu

    Director
  3. Services
    Two scientists look at a computer screen

    Metabolic flux and enrichment studies using MIMOSA

    In this subcore, parameters of cellular and tissue metabolic flux are assessed by incorporation of stable isotope-labeled tracers (e.g., carbon-13, nitrogen-15, or deuterium) into metabolism. The CMC uses the targeted mass isotopomer multi-ordinate spectral analysis (MIMOSA) platform to interpret stable isotope labeling patterns for calculation of rates of discrete steps in glycolytic and mitochondrial metabolism. Such measurements can be used to identify differences in fuel usage (e.g., glycolysis vs. beta-oxidation), and non-oxidative (reductive carboxylation, anaplerosis and cataplerosis) contributions to the TCA cycle.

    Located within Chemical Metabolism Core

    Stephan Siebel, MD, PhD