Y-TRIC imaging systems

Hybrid 128-slice SPECT/CT
Volumetric C-arm X-ray fluoroscopy unit with cone beam imaging capability
3D graphics workstations and servers
Radiochemistry laboratory
MILabs U-SPECT4CT system
Cardiac ultrasound: Philips EPIQ CVxi
VisualSonics Vevo 2100 rodent ultrasound

Hybrid 128-slice SPECT/CT

VERITON CT, Spectrum Dynamics

• New hybrid SPECT CZT 128-slice CT imaging system that allows for focused or whole-body SPECT/CT imaging with high resolution and sensitivity.
• State-of-the-art, full-body 360° digital SPECT/CT system for fully quantitative images for translational research, dosimetry, and a wide range of clinical applications including for diagnostic and prognostic purposes, along with tracking therapeutic interventions.
• The system enables total body imaging, with 200 cm coverage and 80 cm bore size, that incorporates correction for scatter, attenuation, and partial volume effect for improved quantitative accuracy.
• Unique set of 12 digital CZT detectors that automatically move within millimeters of the subject’s body. This allows for maximum sensitivity and resolution. 
• System purchased with an NIH shared instrument grant (S10 OD032277, PI: Sinusas). [Back to top]

Volumetric C-arm X-ray fluoroscopy unit with cone beam imaging capability

Philips Allura Xper, FD20

• State-of-the-art digital ceiling-mounted digital X-ray cone beam fluoroscopy unit can provide cine fluoroscopic imaging and spin 180 degrees to create 3D volumes that can be used for image-directed interventions.
• Operates at between 40–25 kVp, and 1–1,250 mA.

• Provides 60 fps at a resolution of 512 x 512 or 6 fps with a matrix of 2048 x 2048. [Back to top]
   

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3D graphics workstations and servers

• Dedicated rack server with a Windows-based OS (Windows Server 2019) and a shared area network (SAN) disk storage system with >70 TB of onsite storage and expandable cloud storage.
• Satellite computers are used for image and data processing that run Linux and Windows 10 and 11.

InVicro iPACS Discovery data management software

• Perpetual basic software license, vendor-neutral image format collection, reporting engine, cloud-based DICOM server, LDAP, 12-user account package, and 2 administrative user account packages.
• Allows for project-tree data organization with role-based authorization for image study management, data harmonization (storing and indexing) to standardize any data from any imaging modality.
• Vendor-neutral for data organization and can be simplified to allow for direct backup to the Yale AWS cloud storage system.
• Cloud-based DICOM server (AWS) will allow for advanced data-sharing capabilities via public links and iPACS drop zones for internal and external users of the SPECT/CT imaging system.

MIM-SD workstation and software

• Post-processing, quantification, and display of VERITON SPECT/CT reconstructed data.
• MIM-SD provides a diverse set of fusion and nuclear medicine diagnostic viewing and processing tools.
• Supports vendor-neutral multi-modality image fusion for both 3D- and 2D-static scans.
• Fusions are created rapidly using automatic as well as manual techniques.
• The software is intended to receive, transmit, store, retrieve, display, print, and process digital medical images, as well as create, display, and print reports from those images.

Hermes workstation and software

• For post-processing, image segmentation, quantification, and display of VERITON SPECT/CT reconstructed data. 
• This is an alternative vendor-neutral software platform for multi-modality image fusion for both 3D and 2D-static scans. 
• Fusions are created rapidly using automatic as well as manual techniques. 
• The software is intended to receive, transmit, store, retrieve, display, print, and process digital medical images, as well as create, display, and print reports from those images.
• Image processing can also be performed using two dedicated advanced 3D graphic workstations (GE Healthcare AW 4.4), or by using two dedicated GE Xeleris workstations for SPECT/CT image co-registration and analysis. 
• Additionally, a GE AW server (4 TB) provides remote access to images and processing software via Citrix access.
• There are also several high-end PC workstations available for image processing that hold licenses for quantitative image analysis tools, including QLab, PMOD, and EchoInsight. 
• We created two managed Windows virtual servers: one for applications (4 CPUs with 16 GB of memory and 200 GB) and another for data management (4 CPUs with 8 GB of memory and 300 GB). These servers are linked to two TomTec workstations for echocardiographic imaging processing and management. [Back to top]

Radiochemistry laboratory

• Iodination hood
• Biosafety hood
• Lead-lined cabinetry
• Dose preparation area, including shielding and dose calibrator
• Pass-through box into SPECT/CT imaging suite [Back to top]

 MILabs Micro-SPECT⁴CT system

• Hybrid multi-collimator microSPECT/CT system for small-animal imaging
• Dedicated research scanner for small-animal imaging
• Ultra-high resolution (0.25 mm)
• Multiple interchangeable collimators for imaging rats or mice
• Three large NaI detectors
• Capable of performing dynamic microSPECT imaging due to high sensitivity of the system
• MicroCT utilizes cone-beam geometry with a high resolution GOS/CMOS detector (1536 x 1944 pixels with voxel size from 120 to 30 µm)
• Capable of fast CT scanning <8 sec and of cardiac and respiratory gating
• Microfocus X-ray tube is rated at 10 to 65 KV and provides ~15 µm resolution
• Purchased with an NIH shared instrument grant (S10 OD021845-01, PI: Sinusas) [Back to top]

Cardiac ultrasound: Philips EPIQ CVxi

• State-of-the-art ultrasound system that is fully integrated with the Philips Allura Xper FD20 for image-guided interventions.
• Integration kit and cables (EPIQ7Ci integration kit, AVIDIS Smart Cable) enables system interface with our fluoroscopy unit (Allura Xper FD20, Philips)
• 7 transducers
  • X5-1: 3D matrix transducer (1-5 MHz) for transthoracic cardiac imaging (2 probes: one probe for preclinical imaging and one probe for clinical imaging)
  • X7-2: 3D matrix transducer (2-7 MHz) for transthoracic cardiac imaging
  • X8-2t: Transesophageal 3D matrix transducer (2-8 MHz)
  • L12-3: Linear array transducer (3-12 MHz) for vascular imaging
  • L15-7io: Linear array transducer (7-15 MHz) for intraoperative vascular imaging
  • D2CWC: Non-imaging 2 MHz PW/CW Doppler transducer for cardiac applications
  • C5-1 Transducer: Curved array transducer (1-5 MHz) for high performance abdominal applications
• IGT EchoNavigator R3 software and AI license for X8-2t
  • Combining X-ray and 3D TEE echocardiography for guiding interventional procedures
• TrueVue software for photorealistic 3D image-rendering technology
  • Emulates light propagation in tissue
• Cardiac 3D quantification
  • Provides multiplanar reconstruction (MPR) for viewing anatomical planes from 3D volume and new 3D iSlice generation
• Dynamic HeartModel
  • Automated Live 3D quantification tool that calculates both LV and LA volumes, LV, EF, and SV
• TOMTEC Arena
  • Hardware and software for DICOM data management, transfer, and archive
• Installed in 2022 funding from NIH SIG Grant (1 S10 OD028738-01A1, PI: Sinusas) [Back to top]

Rodent ultrasound: VisualSonics Vevo 2100

• High-resolution (30 µm) ultrasound imaging system for rodent imaging. 
• 2D imaging for anatomical visualization and quantification, with enhanced temporal resolution with frame rates up to 740 fps. 
• Capable of pulse-wave and tissue Doppler imaging.
• Purchased with an NIH SIG (PI: Young). [Back to top]