Yale Translational Research Imaging Center (Y-TRIC)

Research Cores Directory
Yale Translational Research Imaging Center (Y-TRIC)

Albert Sinusas, MD

Director

y-tric@yale.edu

About the core

Y-TRIC was established to facilitate translational animal research. The facility centralizes small- and large-animal housing and surgery with state-of-the-art imaging resources. The center focuses on imaging probe and technology development; multimodality anatomic, physiological, and molecular imaging; and image registration and quantification. Training in the Center is supported by an NHLBI-funded T32 program in multimodality molecular and translational cardiovascular imaging. Y-TRIC staff also facilitate multimodality animal imaging at the Yale Magnetic Resonance Research Center (MRRC) and Yale PET Center.

The Yale Translational Research Imaging Center provides:

A centralized state-of-the-art resource for large and small animal image-based experimental research with "turnkey" operation
A centralized location that facilitates the utilization of imaging centers (i.e. MR, PET) for translational research by minimizing transfer distances between surgical/fluoroscopy resources and other imaging centers.
Study design guidance along with vast image-based translational research knowledge and expertise.
Assistance to investigators to hasten regulatory compliance issues.
Assistance, as needed, for surgical interventions, anesthesia monitoring, and long-term monitoring of animals to improve animal welfare.
Cost-effective means for investigators to move their research towards clinical translation.

Core resources include:

Integrated surgical and fluoroscopy suite
Radiochemistry laboratory
Unique hybrid SPECT/64-slice CT scanner
MicroSPECT/CT imaging suite
In vitro and in vivo microCT scanners
3D ultrasound imaging systems
State-of-the-art mouse echo core laboratory
3D graphics workstations

Available to Yale researchers & external researchers

Education & training

Y-TRIC offers education and training programs from postdoctoral fellows to undergraduate students. Follow the links below to learn more about these opportunities.

Postdoctoral training program
Intracardiac imaging and intervention training

Rates

USP rates

FY26, starting July 1, 2025

USP	Internal rate
Interventional imaging suite	$450
Large animal SPECT/CT	$530
Large animal echo	$325
Small animal SPECT/CT	$445
Small animal echo	$180

Core charges

Service	Internal rate
Sterile prep	$84 each
Major pack	$193 each
Minor pack	$155 each
Contrast kit for 570/fluoroscopy	$85 each
Image processing	$160/hr
Technagas Plus System	$85/hr
Prep room	$320/hr
Vet support	$160/hr
Technologist assistance	$105/hr
Technologist assistance (weekend, holiday/recess, overtime)	$200/hr
Advanced hemodynamic monitoring supplies	$67/each
Advanced image processing and data storage	$85/each

Acknowledgment

Publication acknowledgment
If research supported by this research core results in publication, please acknowledge this support by including the following in your publication(s):

“This research was made possible through the utilization of the Yale Translational Research Imaging Center. The equipment was funded in part by NIH grant [*list appropriate number(s): S10RR025555 (NMCT570), S10OD021845 (MILabs VECTOR), S10OD028738 (Philips Epic Ultrasound), S10OD032277 (Spectrum Dynamics)]."

Facility use
"This research was made possible through the utilization of the Yale Translational Research Imaging Center."

Additional contacts

Research fellows

Alaa Alashi, MD, MHS, clinical fellow
Santiago Callegari, MD, hospital resident
Sun-Joo Jan, MD, PhD, clinical fellow
Fatema Tuj Zohora, postdoctoral fellow

Imaging sciences (Image Processing and Analysis [IPAG])

James Duncan, PhD, Ebenezer K. Hunt Professor of Biomedical Engineering and Professor of Radiology and Biomedical Imaging; Department Chair, Biomedical Engineering
Xenophon Papademetris, PhD, Professor of Biomedical Informatics & Data Science, and Radiology & Biomedical Imaging; Associate Director of Biomedical Imaging Data Sciences, Yale Biomedical Imaging Institute; Director of Medical Software and Medical Artificial Intelligence Certificate Program, Department of Biomedical Informatics & Data Science, Yale Biomedical Imaging Institute
Dana Peters, PhD, Professor of Radiology and Biomedical Imaging; Director of Cardiac MRI, Magnetic Resonance Imaging
Lawrence Staib, PhD, Professor of Radiology and Biomedical Imaging, of Biomedical Engineering and of Electrical Engineering; Director of Undergraduate Studies, Biomedical Engineering