In vivo imaging

The PCM provides user access to in vivo imaging instruments housed within imaging clusters at two campus locations. These instruments are available for independent user operation following completion of required instrument and regulatory training. Please set up a consultation if you need assisted imaging.

Yale School of Medicine (LSOG S30)

Bioluminescence, fluorescence, and X-ray co-registration imaging

• PerkinElmer IVIS Spectrum in vivo imaging platform supporting high-sensitivity bioluminescence and fluorescence imaging with spectral unmixing and quantitative analysis for preclinical oncology and immunology studies. The system also enables 3D tomographic imaging, in vitro explant imaging, and plate-based cell assays.
• PerkinElmer IVIS Lumina X5 has capabilities similar to the IVIS Spectrum with X-ray co-registration features.

Yale West Campus (ABC 115)

Bioluminescence, fluorescence, and MRI imaging with life-support systems

• PerkinElmer IVIS Spectrum
• Bruker BioSpec 3T MRI system for high-resolution, non-invasive in vivo imaging of small animals. This platform enables detailed anatomical and functional imaging with excellent soft-tissue contrast and is suitable for longitudinal studies. Capabilities include T1- and T2-weighted anatomical imaging, diffusion-weighted imaging, perfusion and contrast-enhanced MRI, and optional MR spectroscopy. Integrated physiological monitoring and life-support systems support robust and reproducible imaging in disease models, including cancer, neuroscience, and cardiovascular research.

See our user registration requirements and request training.