Instrument/equipment Core/facility: Wu Tsai Institute Microscopy Shared Facility

Leica Viventis dual-view light-sheet microscope

About the instrument

This light-sheet microscope is ideal for high-throughput live imaging of small developing organisms and organoids with sizes ranging from 50 µm to 1 mm. Samples are immersed in an imaging buffer in a cuvette and multiple cuvettes can be used in one experiment, which enables multiple time-lapse experiments, each in a different buffer condition, in one imaging session.

Key features include:

  • Dual illumination and dual detection to minimize depth-induced aberration
  • Two detection-objective blocks (16x and 25x)
  • Resolution: 0.8 and 0.5 µm
  • Four laser lines: 405, 488, 561, and 640 nm
  • CO2 and temperature regulation
Viventis

Available to Yale researchers only