Listing of research core items
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Services
In vivo cancer models
Cell line-derived xenograft (CDX) models, patient-derived xenograft (PDX) models, syngeneic models, genetically engineered mouse models (GEMMS), metastasis models.
Located within Precision Cancer ModelingVish Muthusamy, PhD
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Instrument/equipment
In vivo imaging
The PCM provides user access to in vivo imaging instruments housed within imaging clusters at two campus locations. These instruments are available for independent user operation following completion of required instrument and regulatory training.
Located within Precision Cancer ModelingVish Muthusamy, PhD
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Core/facility
In Vivo Imaging (IVI) Facility
The In Vivo Imaging (IVI) Facility core’s goal is to assist investigators in experimental design and implementation utilizing multiphoton microscopy.
David Gonzalez, MHS LAT
Facility Manager -
Services
Induced pluripotent stem cell (iPSC) production
We reprogram fully differentiated somatic cells to induced pluripotent stem cells (iPSCs).
Located within Human Embryonic/Induced Pluripotent Stem Cell Core -
Instrument/equipment
Instron tensile/compression testing
This instrument performs tensile, compression, flexure/bend, peel, tear, shear, and cyclic tests.
Located within Mechanical and Thermal Analysis Instrumentation Core (MTAIC) -
Instrument/equipment
Instruments for sample preparation
The core houses multiple cryo-sample preparation devices.
Located within Yale CryoEM Resource -
Instrument/equipment
Ion mill
The Hitachi IM4000 can be used for cross-sectioning samples (usually for SEM viewing) or for polishing surfaces.
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Instrument/equipment
Iridium sputtering tool
Iridium is useful for coating samples before electron microscopy.
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Services
Isotope ratio mass spectrometry (IRMS)
Isotope ratio mass spectrometry (IRMS) services
Located within Yale Analytical and Stable Isotope Center (YASIC) -
Core/facility
Irradiator Shared Resource (ISR)
The Irradiator Shared Resource (ISR) provides easy and reliable access to cutting-edge gamma- and x-ray irradiation technologies, services, and scientific consultations for use in basic and translational studies of cancer.
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Core/facility
Keck Mass Spectrometry & Proteomics Resource
We provide efficient and cost-effective proteomics and state-of-the-art small-molecule mass spectrometry-based services.
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Core/facility
Keck Microarray Shared Resource
Microarray platforms available for high-throughput gene-expression detection.