Equipment
Primary contact
About the equipment
The Yale Center for Genome Analysis (YCGA) is a state-of-the-art open access DNA Sequencing Center launched in 2010 on Yale’s West Campus to provide a centralized facility for services, equipment and expertise required for carrying out large-scale sequence analysis studies. YCGA has state-of-the-art equipment for NGS library preparation and sequencing and expert staff who provide a range of genomics services to internal and external users.
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Sequencing
Covaris E210 and R230
Fragment analyzer for sample (DNA/RNA) and library QC
Automation platforms for sample transfer, library prep, & flow cell prep
Quantification of samples, library, and gene expression
Microscope
Computing systems
Tissue culture system
WikiLIMS system
- NovaSeq X plus (Illumina)
- NovaSeq6000 (Illumina)
- MiSeq (Illumina)
- Element AVITI
- Illumina NextSeq2000: This instrument is a walk-in service. Investigators can request training to operate this sequencer. Trained personnel will be allowed to book and operate this instrument. Contact: Ravi Ranjan to schedule training.
Covaris E210 and R230 focus acoustic energy shearing systems for fragmenting DNA and RNA. [Back to top]
- Agilent Fragment analyzer
- Agilent 4200 Tapestation
- Caliper Labchip Gx Touch HT
- Agilent Bioanalyzer
- One Hamilton NGS STAR automation system for library prep
- PerkinElmer Sciclone G3 NGSx system for library prep
- PerkinElmer Janus liquid handling system
- Two Integra VIOFLOW pipetting systems
- One Formulatrix Mantis liquid dispensing system
- Eppendorf epMotion 5075LH automated liquid handler
- Fisher Scientific Kingfisher automation for nucleic acid extraction
- BioRad CFX Opus 96 RT-PCR system
- Roche LightCycler 480 ll qPCR systems
- Molecular Devices SpectraMax II 96/384-well spectrophotometer
- Qubit
- Nanodrop
- Fisher QuantStudio Absolute Q Digital PCR System
- Eco Revolve fluorescent microscope (for tissue culture)
- MERFISH spatial multiomics system (spatial transcriptomics)
- Lenovo performance cluster; with a total of 4,624 cores/CPUs
- Five petabytes of Panasas and Hitachi data systems storage
- More than 50 computer workstations and laptops
State-of-the-art tissue culture system. [Back to top]
WikiLIMS system for tracking of data generation, including sample collection, library preparation, sequencing, and billing. [Back to top]
Available to Yale researchers & external researchers