Spatial genomics and proteomics analysis
Primary contact
About the services
10x Genomics Visium gene expression
With protein co-detection, it is a next-generation molecular profiling solution for classifying tissue based on total mRNA. Map the whole transcriptome with morphological context in FFPE or fresh frozen tissues to discover novel insights into normal development, disease pathology, and clinical translational research.
NanoString GeoMx DSP
The GeoMx Digital Spatial Profiler (DSP) provides morphological context in spatial transcriptomics and spatial proteomics experiments from just one slide. From discovery to translational research, the GeoMx DSP is the most flexible and robust spatial biology solution designed to conform to your ever-changing research needs.
The GeoMx DSP workflow seamlessly integrates with current histology or genomics workflows to help researchers obtain robust and reproducible spatial multiomics data quickly.
Whole tissue sections, FFPE or fresh frozen, can be imaged and stained for RNA or protein. Researchers can then precisely select which tissue compartments or cell types to profile based on the biology, and subsequently count expression levels using either the nCounter Analysis System or an Illumina Sequencer.
Stereo-seq Transcriptomics
Stereo-seq Transcriptomics integrates single-cell profiling with spatial precision on freshfrozen and fixed-frozen or FFPE tissue, leveraging preserved RNA integrity to generate highresolution gene expression maps. A poly-adenylated mRNA capture method supports a wide range of tissue types and species, including human, animal, and plant samples.
- WHOLE-ORGAN SCALE Stereo-seq Large Chip Design (FF)
- Unbiased whole-transcriptome capture at true single-cell resolution
- Species agnostic, supporting human, animal, and plant tissues
- Adjustable spatial bins; Bin 20 approximates a single cell
- H&E or nuclei staining for accurate cell segmentation
Available to Yale researchers & external researchers
Specifications
Sample submission
Please contact Guilin Wang for 10x Visium, Stero-Seq or Nanostring GeoMx service request.
Rates
As of 7/1/26
| Service | Yale user |
|---|---|
| 10x Visium CytAssist HD GEX library prep (without reagents, per section) | $505 |
| 10x Visium CytAssist HD library prep (6.5 mm, per section) | $3,340 |
| 10x Visium CytAssist HD XL GEX library prep (11 mm, per section) | $4,140 |
Non-Yale users: Price upon inquiry.
| Services | Yale user |
|---|---|
| NanoString DSP library prep | $485 |
Non-Yale users: Price upon inquiry.
| Services | Yale user |
|---|---|
| Stero-Seq library prep | upon inquiry |
Non-Yale users: Price upon inquiry.
For more information, contact Guilin Wang.
Invoicing and payment
Visit our invoicing and payment page for instructions.