Services Core/facility: Keck Microarray Shared Resource

Spatial genomics and proteomics analysis

About the services

10x Genomics Visium gene expression

With protein co-detection, it is a next-generation molecular profiling solution for classifying tissue based on total mRNA. Map the whole transcriptome with morphological context in FFPE or fresh frozen tissues to discover novel insights into normal development, disease pathology, and clinical translational research.

NanoString GeoMx DSP

The GeoMx Digital Spatial Profiler (DSP) provides morphological context in spatial transcriptomics and spatial proteomics experiments from just one slide. From discovery to translational research, the GeoMx DSP is the most flexible and robust spatial biology solution designed to conform to your ever-changing research needs.

The GeoMx DSP workflow seamlessly integrates with current histology or genomics workflows to help researchers obtain robust and reproducible spatial multiomics data quickly.

Whole tissue sections, FFPE or fresh frozen, can be imaged and stained for RNA or protein. Researchers can then precisely select which tissue compartments or cell types to profile based on the biology, and subsequently count expression levels using either the nCounter Analysis System or an Illumina Sequencer.

Available to Yale researchers & external researchers

Specifications

Sample submission

Please contact Guilin Wang for 10x Visium or Nanostring GeoMX service request.

Rates

As of 7/1/24

10x Genomics Visium gene expression
ServiceYale userNon-Yale user
CytAssist GEX (2rxn\1 slide 6.5mm)$2,105$2,802
10x Visium CytAssist GEX (2rxn\1 slide 11mm)$4,058$5,420
10x Visium CytAssist GEX (without reagents)$411$635
10x Visium CytAssist HD library prep (per section, 6.5 mm)$3,610$4,741
Nanostring GeoMX
ServicesYale userNon-Yale user
NanoString DSP library prep$637$933

For more information, contact Guilin Wang.

Invoicing and payment

Visit our invoicing and payment page for instructions.