Keck Microarray Shared Resource
Microarray platforms available for high-throughput gene-expression detection.
About the core
The Keck Microarray Shared Resource (KMSR) functions as a shared cost-recovery core facility to provide technical capability and expertise with state-of-the-art instrumentation for biomedical and clinical research at Yale community as well as institutions around the world. The Keck Microarray Resource is committed to:
- Provide timely, high quality data generation and analysis at a competitive cost.
- Work collaboratively with investigators to develop and implement new technologies for their research.
- Educate and train customers in cutting-edge technologies.
We are actively working on bringing more technologies to the Yale community. Started from only microarray analysis more than 10 years ago, the Keck Microarray Resource has evolved and developed into a highly effective and cost-efficient facility offering comprehensive services spanning genomics, epigenomics and transcriptomics applications. Besides the traditional gene expression profiling and SNP genotyping services using Illumina and Affymetrix microarray technologies, we now offer a variety of genomic services including nuclei acid isolation, third generation long read sequencing, spatial genomics and single cell DNA/RNA/protein analysis.
Platforms and services
Affymetrix
- Expression
- Genotyping
- miRNA
Illumina
- Genotyping
- Methylation
10X Genomics single cell and Spatial genomics
- Single cell RNA-seq
- Single cell ATAC-seq
- Single cell multiomics
- Spatial Gene Expression
PacBio and Nanopore long-read sequencing
- Iso-seq
- Whole genome sequencing
- Amplicon sequencing
Nuclei acid isolation
MissionBio single cell DNA analysis
ParseBio single cell RNA-seq
Contacts
Primary contact
Lab Manager
Faculty Director
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Core/Facility
Yale Center for Genome Analysis (YCGA)
The Yale Center for Genome Analysis is a full-service facility dedicated to providing RNA expression profiling, DNA genotyping, and high-throughput sequencing using state-of-the-art technologies.
Primary contact
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Core/Facility
Yale Center for Molecular Discovery
We provide resources for assay development and high-throughput screening with small molecules and arrayed siRNA and sgRNA/CRISPR libraries in biochemical, cell-based and image-based assays (primarily 384-well format).
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Core/Facility
Chemical Metabolism Core
The Chemical Metabolism Core provides resources for measuring islet function, oxygen consumption, and cellular metabolic flux.