Core/facility:
Keck Oligo Synthesis Resource
Oligo pricing
Our pricing schedule as of 07/01/2025
| Cost per base | ||
|---|---|---|
| Synthesis services | Internal user | External user |
25 nanomole-scale PLATES for >47 oligos (DESALTED, ≤65 bases unmodified) (yield of final product will be <25 nmole) | $0.23 | $0.29 |
| 25 nanomole-scale TUBES (DESALTED, ≤65 bases/unmodified)(yield of final product will be <25 nmole) | $0.23 | $0.33 |
| 100 nanomole-scale PLATES for >47 oligos (DESALTED, 1-119 bases/unmodified) (yield of final product will be <100 nmole) | $0.28 | $0.37 |
| 100 nanomole-scale TUBES (DESALTED, 1-119 bases/unmodified)(yield of final product will be <100 nmole) | $0.30 | $0.39 |
| 40 nanomole scale (>119 bases and/or modified) (yield of final product will be <40 nmole) | $0.57 | $0.73 |
| 200 nanomole scale (yield of final product will be <200 nmole) | $0.90 | $1.20 |
| 1.0 micromole scale (yield of final product will be <1.0 µmole) | $2.23 | $2.85 |
| RNA/2’-OMe (1.0 micromole scale) (yield of final product will be <1.0 µmole) | $17.00 | $21.50 |
| Surcharge per oligo | ||
|---|---|---|
| Purification services | Internal user | External user |
| Cartridge purification DNA (40 nmole, 100 nmole, 200 nmole, 1.0 µmole) | $17.25 | $25.50 |
| RP-HPLC DNA (40 nmole, 100 nmole, 200 nmole, 1.0 µmole) (<100 bases) | $60.00 | $75.00 |
| 2’-deprotection/cartridge purification of RNA | $60.00 | $75.00 |
| Hourly fee | ||
|---|---|---|
| Consulting services | Internal user | External user |
| Consult meeting/research (i.e. experimental requests requiring research) | $35.00 | $51.75 |
| Custom processing (i.e. custom synthesizer programming) | Request a quote | |
| Custom processing (i.e. pooling, normalization, special packaging) | Request a quote | |
To request a quote, fill out this spreadsheet and email it to us at oligos@yale.edu
Separate charges for modifications will be added to standard oligo pricing and can be found on our modifier pricing page. Requests for custom synthesis strategies including custom synthesizer setups and special handling/packaging can be accommodated for a nominal fee. Please contact us for pricing.
Want a quote?
Fill out our quote request form and email it to oligos@yale.edu.