Cores Directory
Search for the resources you need to answer your research questions.
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Listing of research core items
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Core/facility
Aberration-Corrected Electron Microscopy (ACEM) Core
Our core's focus is cutting-edge and high-throughput capability in electron microscopy techniques, including TEM, SEM, and FIB.
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Core/facility
YSM Biobank
Contact YSM Biobank for the full spectrum of your biorepository needs: consenting, collection, processing, storage, distribution, data access, grant application support, IRB compliance, and more.
Primary contact
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Core/facility
Keck Biophysical Resource
As of 2026, the Keck Biophysical Resource will no longer be available for services except for NIDA investigators, who will still have access to some technologies.
Ewa Folta-Stogniew, PhD, MSc
Director (Retired) -
Core/facility
Yale Center for Molecular Discovery
We provide resources for assay development and high-throughput screening with small molecules and arrayed siRNA and sgRNA/CRISPR libraries in biochemical, cell-based and image-based assays (primarily 384-well format).
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Core/facility
Chemical Metabolism Core
Previously called the Islet, Oxygen consumption, Mass Isotopomer flux Core (IOMIC), the Chemical Metabolism Core offers targeted and untargeted metabolomics, stable isotope-based metabolic flux analysis, quantitative metabolic panels of central carbon metabolism and adjacent pathways, measurements of cellular bioenergetics, islet isolation and functional studies. Services include study assistance and data analysis.
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Core/facility
Yale Cleanroom Facilities
The University Cleanroom provides a controlled environment that maintains intentionally low concentrations of pollutants to allow for uncontaminated scientific research.
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Core/facility
CMC Live-Cell Imaging Core (CLIC)
Affiliated with the Chemical Metabolism Core (CMC), the Live Cell Imaging Core (CLIC) offers assessments of metabolites, live-cell imaging, biosensor design and delivery, perfusion assays, a library of dyes and biosensors, and more.
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Core/facility
Comparative Pathology Research Core
We offer pathology support for animal-based studies, including histopathology, necropsy, and microbiology, as well as assistance with study design.
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Core/facility
Confocal Microscopy at CCMI
We offer confocal microscopy, two-photon microscopy, light-sheet microscopy, swept-field microscopy, super-resolution imaging, and image analysis services.
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Core/facility
Yale CryoEM Resource
The Yale CryoEM Resource comprises electron microscopes on all 3 campuses: a Titan Krios on West Campus, a Glacios and a Tecnai T12 at Yale School of Medicine, and a Glacios and a Talos L120C on Science Hill.
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Core/facility
Yale CVRC Micro-CT Imaging Core
Dedicated to assisting translation of scientific discoveries from benches to rodent models and to facilitating development of new contrast agents and therapeutic agents.
Zhen Zhuang, MD, MS
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Core/facility
CyTOF Facility
Time-of-flight mass spectrometer for multi-parametric single cell data