Yale Center for Molecular Discovery
We provide resources for assay development and high-throughput screening with small molecules and arrayed siRNA and sgRNA/CRISPR libraries in biochemical, cell-based and image-based assays (primarily 384-well format).
About the core
Our mission is to provide insight into biological mechanisms and disease targets. We provide expertise in compound and siRNA screening and high-content imaging.
Services
- Assay design
- Assay development
- High-throughput screening
- High-throughput microscopy and quantitative image analysis
- Custom liquid transfers
- Self-service lab
- Support for grant applications and other funding opportunities
- Education and training
- Macromolecular X-ray crystallography core
Instrumentation and libraries
Contacts
Location (Directions)
Yale West Campus
600 West Campus Drive
West Haven, CT 06516-0972
Mailing address
Yale Center for Molecular Discovery
P.O. Box 27385
West Haven, CT 06516-0972
Shipping address
300 Heffernan Drive
[Recipient Name], MIC Room 110
West Haven, CT 06516
Primary contact
Executive Director
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Aberration-Corrected Electron Microscopy (ACEM) Core
Our core's focus is cutting-edge and high-throughput capability in electron microscopy techniques, including TEM, SEM, and FIB.
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Keck Biophysical Resource
We offer resources to study the oligomeric state of biomolecular assemblies as well as the thermodynamics and kinetics of macromolecular interactions.
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Core/Facility
BrainWorks
BrainWorks offers safe and repeatable technologies to researchers for cutting-edge studies of human brain function.
General inquiries