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Nov 18th, 2009:. BioImage Suite 3.0beta 3   has been released. See the release announcement for more details.
1075 Posts in 290 Topics by 4443 Members
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Author Topic: smooth  (Read 492 times)
perlaki
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« on: November 02, 2009, 11:21:18 AM »
Why do we use so big smooth in spect analysis (16mm)?
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Xenios Papademetris
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« Reply #1 on: November 03, 2009, 02:08:27 PM »
Usually the SPECT image quality in this context is not high enough to permit localization to anything other than "lobe", smoothing effectively lowers the resolution.

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Dustin
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« Reply #2 on: November 03, 2009, 03:38:05 PM »
As Xenios mentioned, ictal SPECT has a high success rate (upwards of 90%) in localizing the lobe of seizure onset. The success rate drop very quickly when looking for more specific regions. Thus we generally only want to find big blobs in a single lobe when we do this analysis. Smoothing allows this by effectively lowers the resolution. You can see this effect on the sample dataset from spect.yale.edu by lower the smoothing kernel in the SPECT tool. As the kernel becomes smaller, we get less of a big blob and more of small islands through out the brain.

Dustin
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